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KMID : 1145520210070010050
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Journal of Radiopharmaceuticals and Molecular Probes
2021 Volume.7 No. 1 p.50 ~ p.55
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Is it possible to treat COVID-19 pneumonia by low-dose radiation?
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Jeong Jae-Min
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Abstract
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Low-dose radiotherapy has been known to have anti-inflammatory activity and been used for treatment of pneumonia together with anti-serum and sulfanilamide. However, it rapidly discontinued after the development of various antibiotics showing outstanding effect. Recently, it was re-considered to treat COVID-19 which has very limited treatment such as remdesivir and dexamethasone. So, several studies of COVID-19 therapy using low-dose radiation were reported very recently. They showed that low-dose radiation of 0.5~1.5 Gy were useful for decreasing the oxygen consumption and hospitalization period of COVID-19 patients without adverse reaction. Radiopharmaceuticals such as [99mTc]Tc-macroaggregated albumin (MAA) also might be used for low-dose radiotherapy. Administration of vitamin D having anti-inflammatory effect would also be helpful for therapy with synergistic effect.
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KEYWORD
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Radiation therapy, Benign disease, Cancer therapy, COVID-19
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